Second Starr Cancer Consortium Grant Competition

(in alphabetical order by principal investigator)

  • "Cancer Epigenetics: Understanding the "Writers", "Readers" and Functional Readout of Histone Lysine and Arginine Methylation Marks in Human Cancer"
    Principal Investigator:
    •  C. David Allis, PhD, The Rockefeller University

    Co-Principal Investigator:

    • Tom W. Muir, PhD, The Rockefeller University
    • Dinshaw J. Patel, PhD, Memorial Sloan Kettering Cancer Center
    • Robert G. Roeder, PhD, The Rockefeller University
  • "Large-scale Studies of the Epigenetics of Human Leukemia"
    Principal Investigator:
    •  Bradley Bernstein, MD, PhD, Broad Institute of MIT and Harvard

    Co-Principal Investigator:

    • Alexander Meissner, PhD, Broad Institute of MIT and Harvard
    • Ross Levine, MD, Memorial Sloan-Kettering Cancer Center
  • "A Comprehensive Approach to Deciphering ALT in Human Cancers"
    Principal Investigator:
    •  Titia de Lange, PhD, The Rockefeller University

    Co-Principal Investigator:

    • William C. Hahn, MD, PhD, Broad Institute of MIT and Harvard
    • Maria Jasin, PhD, Memorial Sloan-Kettering Cancer Center
    • Neal Lue, MD, PhD, Weill Medical College of Cornell University
    • John J. Petrini, PhD, Memorial Sloan-Kettering Cancer Center
  • "High-throughput cancer gene mutation profiling by single-molecule sequencing"

    Principal Investigator:

    • Levi A. Garraway, MD, PhD, Broad Institute of MIT and Harvard

    Co-Principal Investigator:

    • Marc Ladanyi, MD, Memorial Sloan-Kettering Cancer Center
    • Matthew Meyerson, MD, PhD, Broad Institute of MIT and Harvard
    • Chad Nusbaum, PhD, Broad Institute of MIT and Harvard
  • "Molecular Dissection of Myelodysplastic Syndrome and Myeloproliferative Disease"

    Principal Investigator:

    • D. Gary Gilliland, MD, PhD, Broad Institute of MIT and Harvard

    Co-Principal Investigator:

    • Charles L. Sawyers, MD, Memorial Sloan-Kettering Cancer Center
  • "Studying Tumor Progression and Treatment Resistance Using Focused Re-sequencing of High-value Gene Sets in Mouse Models of Human Lung Adenocarcinoma"

    Principal Investigator:

    • Gregory J. Hannon, PhD, Cold Spring Harbor Laboratory

    Co-Principal Investigators:

    • Tyler Jacks, PhD, Broad Institute of MIT and Harvard
    • Harold Varmus, MD, Memorial Sloan-Kettering Cancer Center
  • "Target Enrichment and Single Molecule Sequencing for Genomic Analysis of Human Tumors"

    Principal Investigator:

    • W. Richard McCombie, PhD, Cold Spring Harbor Laboratory

    Co-Principal Investigator:

    • William Gerald, MD, PhD, Memorial Sloan-Kettering Cancer Center
  • "An Integrative Cancer Genomics Portal"

    Principal Investigator:

    • Jill P. Mesirov, PhD, Broad Institute of MIT and Harvard

    Co-Principal Investigator:

    • Cameron Brennan, MD, Memorial Sloan-Kettering Cancer Center
  • "Histone Phosphorylation: An Epigenetic "Signature" Impacting on Human DNA Damage Response, Genomic Integrity and Oncogenesis"

    Principal Investigator:

    • Dinshaw J. Patel, PhD, Memorial Sloan-Kettering Cancer Center

    Co-Principal Investigator:

    • C. David Allis, PhD, The Rockefeller University
  • "Determining Germline Risk Factors for Lethal Prostate Cancer: the Role of Copy Number Variations in Prostate Cancer Progression"

    Principal Investigators:

    • Mark A. Rubin, MD, Weill Medical College of Cornell University

    Co-Principal Investigators:

    • Francesca Demichelis, PhD, Weill Medical College of Cornell University
    • Charles Lee, PhD, Broad Institute of MIT and Harvard
  • "Identification and Clinical Assessment of Genes that Regulate the Response of Cancers to Rapamycin"

    Principal Investigators:

    • David M. Sabatini, MD, PhD, Broad Institute of MIT and Harvard

    Co-Principal Investigators:

    • Charles L. Sawyers, MD, Memorial Sloan-Kettering Cancer Center
  • "Targeting Inhibitor of Apoptosis Proteins for Cancer Therapy"

    Principal Investigators:

    • Hermann Steller, PhD, The Rockefeller University

    Co-Principal Investigators:

    • Scott Lowe, PhD, Cold Spring Harbor Laboratory
    • Neal Rosen, MD, PhD, Memorial Sloan-Kettering Cancer Center
  • "Mis-regulation of Protein Translation in the Pathogenesis and Treatment of Cancer"

    Principal Investigators:

    • Michael B. Yaffe, PhD, Broad Institute of MIT and Harvard

    Co-Principal Investigators:

    • Steven Carr, PhD, Broad Institute of MIT and Harvard
    • Andrew Koff, PhD, Memorial Sloan-Kettering Cancer Center
  • "Small Molecule Inhibitors of the Ubiquitin Pathway in Antagonizing Skin Carcinogenesis"

    Principal Investigator:

    • Pengbo Zhou, PhD, Weill Medical College of Cornell University

    Co-Principal Investigator:

    • Yueming Li, PhD, Memorial Sloan-Kettering Cancer Center