Eighth Starr Cancer Consortium Grant Competition

  • "Defining the Role of Tumor-Secreted Exosomes in Lymph Node Metastasis"

    Principal Investigator:

    • David Lyden, MD, PhD, Weill Cornell Medical College

    Co-Principal Investigator:

    •  Babak Mehrara, MD, Memorial Sloan Kettering Cancer Center

    Abstract 

  • "Validation of a New Mouse Model System for Castration Resistant Metastatic Prostate Cancer"

    Principal Investigator:

    • Lloyd Trotman, PhD, Cold Spring Harbor Laboratory 

    Co-Principal Investigators:

    • James B. Hicks, PhD, Cold Spring Harbor Laboratory
    • Howard I. Scher, MD, Memorial Sloan Kettering Cancer Center
    • Dana E. Rathkopf, MD, Memorial Sloan Kettering Cancer Center
    • Anuradha Gopalan, MD, Memorial Sloan Kettering Cancer Center
    • Nikolaus Schultz, PhD, Memorial Sloan Kettering Cancer Center

    Abstract 

  • "Regulation of Innate Lymphocytes, Colitis, and Colon Cancer by Transcription Factor Nfil3"

    Principal Investigator:

    • Joseph Sun, PhD, Memorial Sloan Kettering Cancer Center

    Co-Principal Investigators:

    • Andrew Dannenberg, MD, Weill Cornell Medical College
    • Daniel Mucida, PhD, The Rockefeller University 

    Abstract 

  • "Creation of Mouse Models for Fibrolamellar Hepatocellular Carcinoma"

    Principal Investigator:

    • Sanford M. Simon, PhD, The Rockefeller University 

    Co-Principal Investigators:

    • Scott W. Lowe, PhD, Memorial Sloan Kettering Cancer Center
    • Michael P. La Quaglia, MD, Memorial Sloan Kettering Cancer Center

    Abstract 

  • "Inhibition of CDK8/CDK19 as a Therapeutic Strategy for MPNs"

    Principal Investigator:

    • Matthew Shair, PhD, The Broad Institute of MIT & Harvard

    Co-Principal Investigator:

    •  Ross Levine, MD, Memorial Sloan Kettering Cancer Center

    Abstract 

  • "The Impact of the Gastric Microbiome on Gastric Cancer Development"

    Principal Investigator:

    • Manish Shah, MD, Weill Cornell Medical College

    Co-Principal Investigators:

    • Adam Bass, MD, The Broad Institute of MIT & Harvard
    • Doron Betel, PhD, Weill Cornell Medical College
    • Eric Pamer, MD, Memorial Sloan Kettering Cancer Center
    • Nikolas Schultz, PhD, Memorial Sloan Kettering Cancer Center

    Abstract 

  • "Discovery and Validation of Tumor Suppressor Genes in Colorectal Cancer Using a Novel Cross Species Approach"

    Principal Investigator:

    • Norbert Perrimon, PhD, The Broad Institute of MIT & Harvard

    Co-Principal Investigators:

    • Lukas Dow, PhD, Weill Cornell Medical College
    • Christina Leslie, PhD, Memorial Sloan Kettering Cancer Center
    • Scott Lowe, PhD, Memorial Sloan Kettering Cancer Center

    Abstract 

  • "Designing Sinefungin Scaffolds as Specific Protein Methyltransferase Inhibitors"

    Principal Investigator:

    • Minkui Luo, PhD, Memorial Sloan Kettering Cancer Center 

    Co-Principal Investigators:

    • John Chodera, PhD, Memorial Sloan Kettering Cancer Center
    • Angela Koehler, PhD, The Broad Institute of MIT & Harvard
    • Dinshaw Patel, PhD, Memorial Sloan Kettering Cancer Center
    • Lei Shi, PhD, Weill Cornell Medical College

    Abstract 

  • "Threshold Effects and Non-canonical Functions of the Tumor Suppressor BRCA2 and Interacting Proteins RAD51 and DSS1"

    Principal Investigator:

    • Maria Jasin, PhD, Memorial Sloan Kettering Cancer Center

    Co-Principal Investigators:

    • Agata Smogorzewska, MD, PhD, The Rockefeller University
    • William Holloman, PhD, Weill Cornell Medical College

    Abstract 

  • "Identification of Tumor Cell and Microenvironmental Determinants of Response to Immune Checkpoint Blockade in Lung Cancer"

    Principal Investigator:

    • Timothy Chan, MD, PhD, Memorial Sloan Kettering Cancer Center

    Co-Principal Investigators:

    • Peter Hammerman, MD, The Broad Institute of MIT & Harvard
    • Charles Rudin, MD, PhD, Memorial Sloan Kettering Cancer Center
    • Jedd Wolchok, MD, PhD, Memorial Sloan Kettering Cancer Center

    Abstract 

  • "Understanding and Targeting Spliceosomal-Mutation Hematopoietic Malignancies"

    Principal Investigator:

    • Omar Abdel-Wahab, MD, Memorial Sloan Kettering Cancer Center

    Co-Principal Investigators:

    • Benjamin Ebert, MD, PhD, The Broad Institute of MIT & Harvard
    • Adrian Krainer, PhD, Cold Spring Harbor Laboratory
    Abstract