Ninth Starr Cancer Consortium Grant Competition
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"Mechanism-Based Targeting of RNA Binding Protein Networks for Chemo-Sensitization in Non-Small Cell Lung Cancer (NSCLC)"
Principal Investigator:
- Michael B. Yaffe, MD, PhD, The Broad Institute of MIT & Harvard
Co-Principal Investigators:
- Robert B. Darnell, MD, PhD, The Rockefeller University
- Michael T. Hemann, PhD, The Broad Institute of MIT & Harvard
Abstract
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"Targeting the Chromatin Reader Protein TRIM33 as Epigenetic Therapy in B Cell Neoplasms"
Principal Investigator:
- Christopher R. Vakoc, MD, PhD, Cold Spring Harbor Laboratory
Co-Principal Investigators:
- James E. Bradner, MD, The Broad Institute of MIT & Harvard
- Nathanael S. Gray, PhD, The Broad Institute of MIT & Harvard
- Dinshaw Patel, PhD, Memorial Sloan Kettering Cancer Center
Abstract
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"The Paternal Germline as a Source of de novo Cancer Risk in Offspring"
Principal Investigator:
- Marco Seandel, MD, PhD, Weill Cornell Medical College
Co-Principal Investigators:
- Zsofia Stadler, MD, Memorial Sloan Kettering Cancer Center
- Michael Wigler, PhD, Cold Spring Harbor Laboratory
Abstract
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"Personalized Immunotherapy for the Treatment of Hematological Malignancies"
Principal Investigator:
- Ann Mullally, MD, The Broad Institute of MIT & Harvard
Co-Principal Investigators:
- Omar Abdel-Wahab, MD, Memorial Sloan Kettering Cancer Center
- Timothy Chan, MD, PhD, Memorial Sloan Kettering Cancer Center
- Taha Merghoub, PhD, Memorial Sloan Kettering Cancer Center
Abstract
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"Circulating Exosomal microRNA as Biomarkers of Medulloblastoma Progression, Metastasis, and Recurrence"
Principal Investigator:
- David Lyden, MD, PhD, Weill Cornell Medical College
Co-Principal Investigators:
- Ira Dunkel, MD, Memorial Sloan Kettering Cancer Center
- Kim Kramer, MD, Memorial Sloan Kettering Cancer Center
- Praveen Raju, MD, PhD, Weill Cornell Medical College
- Sohail Tavazoie, MD, PhD, The Rockefeller University
- Haiying Zhang, PhD, Weill Cornell Medical College
Abstract
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"Translating Molecular Profiles into Clinical Biomarkers Using Spatially Defined RNA Sequencing in situ"
Principal Investigator:
- Je H. Lee, MD, PhD, Cold Spring Harbor Laboratory
Co-Principal Investigators:
- Timothy Chan, MD, PhD, Memorial Sloan Kettering Cancer Center
- Molly Hammell, PhD, Cold Spring Harbor Laboratory Laboratory
Abstract
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"Translation Regulation in Acute Myeloid Leukemia"
Principal Investigator:
- Michael Kharas, PhD, Memorial Sloan Kettering Cancer Center
Co-Principal Investigators:
- Leandro Cerchietti, MD, Weill Cornell Medical College
- Christopher Park, MD, PhD, Memorial Sloan Kettering Cancer Center
Abstract
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"Epigenetic Control of DNA Transposition in Embryonal Cancers"
Principal Investigator:
- Alex Kentsis, MD, PhD, Memorial Sloan Kettering Cancer Center
Co-Principal Investigators:
- Bradley Bernstein, MD, PhD, The Broad Institute of MIT & Harvard
- Christopher Mason, PhD, Weill Cornell Medical College
Abstract
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"A Massively Parallel Protein Synthesis Platform for Functional Screening of Cancer Proteomes"
Principal Investigator:
- Samie Jaffrey, MD, PhD, Weill Cornell Medical College
Co-Principal Investigators:
- Fabien Campagne, PhD, Weill Cornell Medical College
- Jedd Wolchok, MD, PhD, Memorial Sloan Kettering Cancer Center
Abstract
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"Telomere Crisis and Chromosome Shattering in Cancer"
Principal Investigator:
- Titia de Lange, PhD, The Rockefeller University
Co-Principal Investigators:
- Levi Garraway, MD, PhD, The Broad Institute of MIT & Harvard
- Achim Jungbluth, MD, Memorial Sloan Kettering Cancer Center
Abstract
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"Elucidating the Etiologic Role of Linker Histone Mutations in Hematologic Malignancy"
Principal Investigator:
- Ethel Cesarman, MD, PhD, Weill Cornell Medical College
Co-Principal Investigators:
- C. David Allis, PhD, The Rockefeller University
- Ari M. Melnick, MD, Weill Cornell Medical College
- Robert G. Roeder, PhD, The Rockefeller University
Abstract