2011 Publications

Research supported by Starr Cancer Consortium awards is reported in the following publications. The Starr Cancer Consortium is funded by the Starr Foundation.

Do Airway Epithelium Air-liquid Cultures Represent the In Vivo Airway Epithelium Transcriptome?

Dvorak A, Tilley AE, Shaykhiev R, Wang R, Crystal RG.

American Journal of Respiratory Cell Molecular Biology
Aerobic glycolysis: meeting the metabolic requirements of cell proliferation.

Lunt SY, Vander Heiden MG.

Annual Review of Cell Developmental Biology
Mirtrons: microRNA biogenesis via splicing.

Westholm JO, Lai EC.

Biochimie
Haploinsufficiency for ribosomal protein genes causes selective activation of p53 in human erythroid progenitor cells.

Dutt S, Narla A, Lin K, Mullally A, Abayasekara N, Megerdichian C, Wilson FH, Currie T, Khanna-Gupta A, Berliner N, Kutok JL, Ebert BL.

Blood
Common breast cancer susceptibility alleles are associated with tumor subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2.

Mulligan AM, Couch FJ, Barrowdale D, Domchek SM, Eccles D, et al.

Breast Cancer Research
Reciprocal Feedback Regulation of PI3K and Androgen Receptor Signaling in PTEN-Deficient Prostate Cancer.

Carver BS, Chapinski C, Wongvipat J, Hieronymus H, Chen Y, Chandarlapaty S, Arora VK, Le C, Koutcher J, Scher H, Scardino PT, Rosen N, Sawyers CL.

Cancer Cell
Identification of PHLPP1 as a tumor suppressor reveals the role of feedback activation in PTEN-mutant prostate cancer progression.

Chen M, Pratt CP, Zeeman ME, Schultz N, Taylor BS, O'Neill A, Castillo-Martin M, Nowak DG, Naguib A, Grace DM, Murn J, Navin N, Atwal GS, Sander C, Gerald WL, Cordon-Cardo C, Newton AC, Carver BS, Trotman LC.

Cancer Cell
JAK2V617F-Mediated Phosphorylation of PRMT5 Downregulates Its Methyltransferase Activity and Promotes Myeloproliferation.

Liu F, Zhao X, Perna F, Wang L, Koppikar P, Abdel-Wahab O, Harr MW, Levine RL, Xu H, Tefferi A, Deblasio A, Hatlen M, Menendez S, Nimer SD.

Cancer Cell
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation.

Moran-Crusio K, Reavie L, Shih A, Abdel-Wahab O, Ndiaye-Lobry D, Lobry C, Figueroa ME, Vasanthakumar A, Patel J, Zhao X, Perna F, Pandey S, Madzo J, Song C, Dai Q, He C, Ibrahim S, Beran M, Zavadil J, Nimer SD, Melnick A, Godley LA, Aifantis I, Levine RL.

Cancer Cell
Gammaherpesvirus and lymphoproliferative disorders in immunocompromised patients.

Cesarman, E.

Cancer Letters
Small RNA sequencing and functional characterization reveals microRNA-143 tumor suppressor activity in liposarcoma.

Ugras S, Brill ER, Jacobsen A, Hafner M, Socci N, Decarolis PL, Khanin R, O'Connor RB, Mihailovic A, Taylor BS, Sheridan R, Gimble J, Viale A, Crago A, Antonescu CR, Sander C, Tuschl T, Singer S.

Cancer Research
Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP.

Hafner M, Landthaler M, Burger L, Khorshid M, Hausser J, Berninger P, Rothballer A, Ascano M Jr, Jungkamp AC, Munschauer M, Ulrich A, Wardle GS, Dewell S, Zavolan M, Tuschl T.

Cell
Role for Dpy-30 in ES Cell-Fate Specification by Regulation of H3K4 Methylation within Bivalent Domains.

Jiang H, Shukla A, Wang X, Chen WY, Bernstein BE, Roeder RG.

Cell
Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes.

Klein IA, Resch W, Jankovic M, Oliveira T, Yamane A, Nakahashi H, Di Virgilio M, Bothmer A, Nussenzweig A, Robbiani DF, Casellas R, Nussenzweig MC.

Cell
The Eph-receptor A7 is a soluble tumor suppressor for follicular lymphoma.

Oricchio E, Nanjangud G, Wolfe AL, Schatz JH, Mavrakis KJ, Jiang M, Liu X, Bruno J, Heguy A, Olshen AB, Socci ND, Teruya-Feldstein J, Weis-Garcia F, Tam W, Shaknovich R, Melnick A, Himanen JP, Chaganti RS, Wendel HG.

Cell
Recognition of a Mononucleosomal Histone Modification Pattern by BPTF via Multivalent Interactions.

Ruthenburg AJ, Li H, Milne TA, Dewell S, McGinty RK, Yuen M, Ueberheide B, Dou Y, Muir TW, Patel DJ, Allis CD.

Cell
A Poised Chromatin Platform for TGF-beta Access to Master Regulators.

Xi Q, Wang Z, Zaromytidou AI, Zhang XH, Chow-Tsang LF, Liu JX, Kim H, Barlas A, Manova-Todorova K, Kaartinen V, Studer L, Mark W, Patel DJ, Massague J.

Cell
Targeted cancer therapy: what if the driver is just a messenger?

Schatz JH, Wendel HG.

Cell Cycle
Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines.

Gottwein E, Corcoran DL, Mukherjee N, Skalsky RL, Hafner M, Nusbaum JD, Shamulailatpam P, Love CL, Dave SS, Tuschl T, Ohler U, Cullen BR.

Cell Host and Microbe
TET Family Proteins and Their Role in Stem Cell Differentiation and Transformation.

Cimmino, L; Abdel-Wahab, O; Levine, RL; Aifantis, I.

Cell Stem Cell

1 2 3 4