First Starr Cancer Consortium Grant Competition

  • "Mechanisms of miRNA biogenesis and mRNA targeting and molecular interventions to modulate miRNA pathways in normal and disease states"

    Principal Investigator:

    • Thomas Tuschl, PhD, Rockefeller University

    Co-Principal Investigators:

    • Dinshaw Patel, PhD, Memorial Sloan-Kettering Cancer Center
    • Eric Holland, MD, PhD, Memorial Sloan-Kettering Cancer Center
    • Hakim Djaballah, PhD, Memorial Sloan-Kettering Cancer Center
  • "The Sarcoma Genome Project Phase II: A Comprehensive Molecular Characterization of Soft Tissue Sarcoma to Identify Subtype Specific Therapies"

    Principal Investigator:

    • Samuel Singer, MD, Memorial Sloan-Kettering Cancer Center

    Co-Principal Investigators:

    • Chris Sander, PhD, Memorial Sloan-Kettering Cancer Center
    • Marc Ladanyi, MD, Memorial Sloan-Kettering Cancer Center
    • Thomas Tuschl, PhD, Rockefeller University
    • Matthew Meyerson, MD, PhD, The Broad Institute of Harvard & MIT
  • "Targeting the cancer stem cell niche for novel cancer therapeutics"

    Principal Investigator:

    • Stuart Schreiber, PhD, The Broad Institute of Harvard & MIT

    Co-Principal Investigators:

    • David Scadden, MD, The Broad Institute of Harvard & MIT
    • Gary Gilliland, MD, PhD, The Broad Institute of Harvard & MIT
    • Malcolm Moore, DPhil, Memorial Sloan-Kettering Cancer Center
  • "Dendritic Cell Targeting: A Novel Approach to Tumor Vaccination"

    Principal Investigator:

    • Jeffrey Ravetch, MD, PhD, Rockefeller University

    Co-Principal Investigators:

    • Ralph Steinman, MD, Rockefeller University
    • Alan Houghton, MD, Memorial Sloan-Kettering Cancer Center
    • James Allison, PhD, Memorial Sloan-Kettering Cancer Center
  • "Testing and Validating High Throughput Analysis of FFPE Samples: Transforming the Scope of Investigations into the Genomic Basis of Cancer"

    Principal Investigator:

    • Scott Powers, PhD, Cold Spring Harbor Laboratory

    Co-Principal Investigators:

    • William Gerald, MD, PhD, Memorial Sloan-Kettering Cancer Center
    • Robert Lucito, PhD, Cold Spring Harbor Laboratory
    • Adam Olshen, PhD, Memorial Sloan-Kettering Cancer Center
    • Agnes Viale, PhD, Memorial Sloan-Kettering Cancer Center
  • "Breast Cancer Protective Alleles by Whole Genome Association and Copy Number Analysis"

    Principal Investigator:

    • Kenneth Offit, MD, Memorial Sloan-Kettering Cancer Center

    Co-Principal Investigators:

    • David Altshuler, MD, PhD, The Broad Institute of Harvard & MIT
    • Daniel Haber, MD, PhD, The Broad Institute of Harvard & MIT
  • "Tumor development and treatment of EBV-associated lymphomas in immune competent humanized mice"

    Principal Investigator:

    • Christian Munz, PhD, Rockefeller University

    Co-Principal Investigator:

    • Ethel Cesarman, MD, PhD, Weill Medical College of Cornell University
  • "Role of Alternative Splicing in Regulating Cancer-Cell Metabolism"

    Principal Investigator:

    • Adrian Krainer, PhD, Cold Spring Harbor Laboratory

    Co-Principal Investigator:

    • Lewis Cantley, PhD, The Broad Institute of Harvard & MIT
  • "Design and application of biocompatible dendrimers for cancer therapy"

    Principal Investigator:

    • Samie Jaffrey, MD, PhD, Weill Medical College of Cornell University

    Co-Principal Investigator:

    • David Gin, PhD, Memorial Sloan-Kettering Cancer Center
  • "Application of Genomics to Developmental Therapeutics of Melanoma"

    Principal Investigator:

    • Alan N. Houghton, MD, Memorial Sloan-Kettering Cancer Center

    Co-Principal Investigators:

    • Levi Garraway, MD, PhD, The Broad Institute of Harvard & MIT
    • Todd R. Golub, MD, The Broad Institute of Harvard & MIT
    • Scott Powers, PhD, Cold Spring Harbor Laboratory
    • Neal Rosen, MD, PhD, Memorial Sloan-Kettering Cancer Center
    • Gary Schwartz, MD, Memorial Sloan-Kettering Cancer Center
  • "Identification of Subclasses of Cerebellar Granule Neuron Progenitor Cells, and their Potential to form Pediatric Brain Tumors"

    Principal Investigator:

    • Mary E. Hatten, PhD, Rockefeller University

    Co-Principal Investigator:

    • Linda Van Aelst, PhD, Cold Spring Harbor laboratory
  • "Comparative oncogenomics to discover oncogene synthetic lethality"

    Principal Investigator:

    • William C. Hahn, MD, PhD, The Broad Institute of Harvard & MIT

    Co-Principal Investigators:

    • Greg Hannon, PhD, Cold Spring Harbor Laboratory
    • Scott Lowe, PhD, Cold Spring Harbor Laboratory
  • "Discovering Small Molecule Inhibitors of MYC and RAS"

    Principal Investigator:

    • Todd R. Golub, MD, The Broad Institute of Harvard & MIT

    Co-Principal Investigators:

    • Michael A. Foley, PhD, The Broad Institute of Harvard & MIT
    • Derek S. Tan, PhD, Memorial Sloan-Kettering Cancer Center
  • "Epithelial Stem Cells in Lung Cancer and COPD"

    Principal Investigator:

    • Ronald G. Crystal, MD, Weill Medical College of Cornell University

    Co-Principal Investigator:

    • Malcolm A.S. Moore, DPhil, Memorial Sloan-Kettering Cancer Center
  • "Mechanism of tumor progression in mouse and human familial GIST"
    Principal Investigator:
    •  Peter Besmer, PhD, Memorial Sloan-Kettering Cancer Center

    Co-Principal Investigator:

    • Michael Wigler, PhD, Cold Spring Harbor Laboratory
    • Cristina Antonescu, MD, Memorial Sloan-Kettering Cancer Center
    • Joseph Scandura, MD, PhD, Weill Medical College of Cornell University
  • "Translational Studies of Neural Mechanisms of Chemotherapy-induced Cognitive Changes"
    Principal Investigator:
    • Tim Ahles, PhD, Memorial Sloan-Kettering Cancer Center

    Co-Principal Investigator:

    • David Silbersweig, MD, Weill Medical College of Cornell University