Twelfth Starr Cancer Consortium Grant Competition
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APOBEC Mutagenesis in Bladder Cancer: Mechanisms and Therapeutic Opportunities
Principal Investigator:
- Bishoy Morris Faltas, MD - Weill Cornell Medicine
Co-Principal Investigators:
- John Maciejowski, PhD - Memorial Sloan Kettering Cancer Center
- Eliezer M. Van Allen, MD - The Broad Institute of MIT and Harvard
Abstract
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Defining prostate cancer cells of origin through single cell profiling
Principal Investigator:
- Charles Sawyers, MD - Memorial Sloan Kettering Cancer Center
Co-Principal Investigator:
- Orit Rozenblatt-Rosen, PhD - The Broad Institute of MIT and Harvard
Abstract
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Genomic instability in the chromosomal context of physiological DNA double-strand break formation
Principal Investigator:
- Jessica Tyler, PhD - Weill Cornell Medicine
Co-Principal Investigators:
- Scott Keeney, PhD - Memorial Sloan Kettering Cancer Center
- Jayanta Chaudhuri, PhD - Memorial Sloan Kettering Cancer Center
- Barry Sleckman, MD, PhD - Weill Cornell Medicine
- Marcin Imielinski, MD, PhD - Weill Cornell Medicine
Abstract
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Identification of transcriptional determinants of asparaginase sensitivity in leukemias
Principal Investigator:
- Kivanc Birsoy, PhD - The Rockefeller University
Co-Principal Investigators:
- Omar Abdel-Wahab, MD - Memorial Sloan Kettering Cancer Center
- Robert G Roeder, PhD - The Rockefeller University
- Giorgio Inghirami, MD - Weill Cornell Medicine
Abstract
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Real-time imaging of metabolite deregulation in cancer
Principal Investigator:
- Samie R. Jaffrey, MD, PhD - Weill Cornell Medicine
Co-Principal Investigator:
- Lydia Finley, PhD - Memorial Sloan Kettering Cancer Center
Abstract
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Lynch syndrome Colorectal Cancer Immunoprevention using Recurrent Neoantigen Peptide Vaccination
Principal Investigator:
- Steven Lipkin, MD, PhD - Weill Cornell Medicine
Co-Principal Investigators:
- Gad Getz, PhD - The Broad Institute of MIT and Harvard
- Catherine Wu, MD - The Broad Institute of MIT and Harvard
- Zsofia Stadler, MD - Memorial Sloan Kettering Cancer Center
- Nir Hacohen, PhD - The Broad Institute of MIT and Harvard
Abstract
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Using morphological pharmacodynamic markers to analyze drug sensitivity, resistance, and toxicity
Principal Investigator:
- Tarun M. Kapoor, PhD - The Rockefeller University
Co-Principal Investigator:
- Anne E. Carpenter, PhD - The Broad Institute of MIT and Harvard
Abstract
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The function and regulation of MiT/TFE activation in autophagy and pancreatic ductal adenocarcinoma
Principal Investigator:
- Yi-Chieh Nancy Du, PhD - Weill Cornell Medicine
Co-Principal Investigators:
- Yueming Li, PhD - Memorial Sloan Kettering Cancer Center
- Xuejun Jiang, PhD - Memorial Sloan Kettering Cancer Center
Abstract
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Imaging and targeting glycolytically driven oxidative stress using ascorbate
Principal Investigator:
- Kayvan R. Keshari, PhD - Memorial Sloan Kettering Cancer Center
Co-Principal Investigators:
- Lewis C. Cantley, PhD - Weill Cornell Medicine
- Manish Shah, MD - Weill Cornell Medicine
Abstract