Sixteenth Starr Cancer Consortium Grant Competition
Competing Project Renewal Awards
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Mechanisms of dynamic chromatin reorganization regulating B-cell differentiation and Lymphomagenesis
Principal Investigator:
- Steven Josefowicz, PhD - Weill Cornell Medicine
Co-Principal Investigators:
- Christina Leslie, PhD - Memorial Sloan Kettering Cancer Center
- Ari Melnick, MD - Weill Cornell Medicine
- Shixin Liu, PhD - The Rockefeller University
Abstract
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Determining and targeting evolutionary trajectories driving bladder cancer
Principal Investigator:
- Dawid Nowak, PhD - Weill Cornell Medicine
Co-Principal Investigators:
- David Solit, MD - Memorial Sloan Kettering Cancer Center
- Adam Siepel, PhD - Cold Spring Harbor Laboratory
Abstract
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Defining the gene regulatory response and pathways for acquired resistance to CDK inhibitor treatment in hormone receptor positive breast cancer
Principal Investigator:
- Viviana Risca, PhD - The Rockefeller University
Co-Principal Investigators:
- Sarat Chandarlapaty, MD, PhD - Memorial Sloan Kettering Cancer Center
- Andrew Koff, PhD - Memorial Sloan Kettering Cancer Center
Abstract
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Defining the role of stress-induced changes in the IgG-gut microbiome-neutrophil axis during breast cancer progression and metastasis
Principal Investigator:
- Melody Zeng, PhD - Weill Cornell Medicine
Co-Principal Investigators:
- Irina Matei, PhD - Weill Cornell Medicine
- Mikala Egeblad, PhD - Cold Spring Harbor Laboratory
Abstract
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Identifying acquired vulnerabilities driven by lineage plasticity and drug resistance in CRC
Principal Investigator:
- Lukas Dow, PhD - Weill Cornell Medicine
Co-Principal Investigator:
- Karuna Ganesh, MD, PhD - Memorial Sloan Kettering Cancer Center
Abstract
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Sequestration of transcriptional regulators by the lenalidomide–cereblon complex for targeting myeloid leukemia
Principal Investigator:
- Christina Woo, PhD - The Broad Institute of MIT and Harvard
Co-Principal Investigator:
- Michael Kharas, PhD - Memorial Sloan Kettering Cancer Center
Abstract
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Targeting cytidine deaminase-induced chromosomal instability as a driver of metastasis in bladder cancer
Principal Investigator:
- Bishoy Faltas, MD - Weill Cornell Medicine
Co-Principal Investigators:
- Samuel Bakhoum, MD, PhD - Memorial Sloan Kettering Cancer Center
- Vivek Mittal, PhD - Weill Cornell Medicine
Abstract
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The influence of homologous recombination deficiency on tumor immunity and immunotherapy efficacy
Principal Investigator:
- Nadeem Riaz, MD - Memorial Sloan Kettering Cancer Center
Co-Principal Investigators:
- Jorge Reis-Filho, MD, PhD - Memorial Sloan Kettering Cancer Center
- Lorenzo Galluzzi, PhD - Weill Cornell Medicine
Abstract