Fifth Starr Cancer Consortium Grant Competition
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"A Multidisciplinary Approach to the Study of an Oncogenic microRNA Cluster"
Principal Investigator:
- Andrea Ventura, MD, PhD, Memorial Sloan-Kettering Cancer Center
Co-Principal Investigators:
- Robert Darnell, MD, PhD, The Rockefeller University
- Doron Betel, PhD, Weill Cornell Medical College
Abstract
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"Proteomic Analysis of Proximal Pulmonary Venous Blood Identifies Biomarkers for Non-Small Cell Lung Cancer"
Principal Investigator:
- Brendon Stiles, MD, Weill Cornell Medical College
Co-Principal Investigators:
- Raffaella Sordella, PhD, Cold Spring Harbor Laboratory
- Darryl Pappin, PhD, Cold Spring Harbor Laboratory
- Olivier Elemento, PhD, Weill Cornell Medical College
Abstract
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"Discovery of Prostate Cancer Tumor Suppressors and Treatment Biomarkers through in vivo RNA Interference Screens"
Principal Investigator:
- Charles Sawyers, MD, Memorial Sloan-Kettering Cancer Center
Co-Principal Investigator:
- Gregory Hannon, PhD, Cold Spring Harbor Laboratory
Abstract
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"Functions and Mechanisms of E-box-binding Transcription Factors in AML 1-ETO-mediated Leukemogenesis"
Principal Investigator:
- Robert Roeder, PhD, The Rockefeller University
Co-Principal Investigators:
- Dinshaw Patel, PhD, Memorial Sloan-Kettering Cancer Center
- Stephen Nimer, MD, Memorial Sloan-Kettering Cancer Center
Abstract
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"Genomic and Epigenetics Changes Occurring During Carcinogenesis: A Fly Perspective"
Principal Investigator:
- Norbert Perrimon, PhD, The Broad Institute of MIT and Harvard
Co-Principal Investigator:
- Gregory Hannon, PhD, Cold Spring Harbor Laboratory
Abstract
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"Transforming Genomics Data Visualization for Cancer Research"
Principal Investigator:
- Jill P. Mesirov, PhD, The Broad Institute of MIT and Harvard
Co-Principal Investigators:
- Chris Sander, PhD, Memorial Sloan-Kettering Cancer Center
- Mark Rubin, MD, Weill Cornell Medical College
Abstract
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"Genomewide Discovery of Novel Cancer Predisposing Mutations"
Principal Investigator:
- Steven Lipkin, MD, PhD, Weill Cornell Medical College
Co-Principal Investigators:
- David Altshuler, MD, PhD, The Broad Institute of MIT and Harvard
- Mark Daly, PhD, The Broad Institute of MIT and Harvard
- Kenneth Offit, MD, Memorial Sloan-Kettering Cancer Center
Abstract
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"Developing Fascin Inhibitors to Block Tumor Metastasis"
Principal Investigator:
- Xin-Yun Huang, PhD, Weill Cornell Medical College
Co-Principal Investigators:
- J. David Warren, PhD, Weill Cornell Medical College
- J. Fraser Glickman, PhD, The Rockefeller University
Abstract
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"Genome Wide Profiling of Single Cells for Diagnosis and Monitoring in Prostate Cancer"
Principal Investigator:
- James Hicks, PhD, Cold Spring Harbor Laboratory
Co-Principal Investigators:
- Charles Sawyers, MD, Memorial Sloan-Kettering Cancer Center
- Howard Scher, MD, Memorial Sloan-Kettering Cancer Center
- Michael Wigler, PhD, Cold Spring Harbor Laboratory
Abstract
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"Novel Approaches to Target High Grade Ovarian Cancers"
Principal Investigator:
- William C. Hahn, MD, PhD, The Broad Institute of MIT and Harvard
Co-Principal Investigators:
- Malcolm A.S. Moore, DPhil, Memorial Sloan-Kettering Cancer Center
- Robert Benezra, PhD, Memorial Sloan-Kettering Cancer Center
- Sangeeta Bhatia, MD, PhD, The Broad Institute of MIT and Harvard
Abstract
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"An Integrated Host and Pathogen Genetic Strategy to Elucidate the Mechanism of Action of BCG in Therapy of Bladder Cancer"
Principal Investigator:
- Michael Glickman, MD, Memorial Sloan-Kettering Cancer Center
Co-Principal Investigators:
- William C. Hahn, MD, PhD, The Broad Institute of MIT and Harvard
- David Root, PhD, The Broad Institute of MIT and Harvard
- Eric Rubin, MD, PhD, The Broad Institute of MIT and Harvard
Abstract
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"Systematic Studies of Resistance to Targeted Anticancer Therapeutics and Combinations"
Principal Investigator:
- Levi Garraway, MD, PhD, The Broad Institute of MIT and Harvard
Co-Principal Investigators:
- Boris Bastian, MD, PhD, Memorial Sloan-Kettering Cancer Center
- Gary K. Schwartz, MD, Memorial Sloan-Kettering Cancer Center
- David Root, PhD, The Broad Institute of MIT and Harvard
- Michael Berger, PhD, Memorial Sloan-Kettering Cancer Center
Abstract
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"Novel Treatment Strategies for Glioblastoma Using AAV-mediated CNS Gene Transfer of Monoclonal Antibodies"
Principal Investigator:
- Ronald Crystal, MD, Weill Cornell Medical College
Co-Principal Investigator:
- Viviane Tabar, MD, Memorial Sloan-Kettering Cancer Center
Abstract
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"Activation of Natural RTK Inhibitors in Cancer Therapy"
Principal Investigator:
- Luca Cartegni, PhD, Memorial Sloan-Kettering Cancer Center
Co-Principal Investigator:
- Raffaella Sordella, PhD, Cold Spring Harbor Laboratory
Abstract
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"Bromodomain Inhibition as Targeted Therapy in Acute Myeloid Leukemia"
Principal Investigators:
- James Bradner, MD, The Broad Institute of MIT & Harvard
Co-Principal Investigators:
- Stephen D. Nimer, MD, Memorial Sloan-Kettering Cancer Center
- Christopher R. Vakoc, MD, PhD, Cold Spring Harbor Laboratory
Abstract
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"Investigation of the ATRX-Daxx Chromatin-remodeling Complex in Pancreatic Neuroendocrine Tumors"
Principal Investigator:
- C. David Allis, PhD, The Rockefeller University
Co-Principal Investigators:
- Laura Tang, MD, PhD, Memorial Sloan-Kettering Cancer Center
- James Hsieh, MD, PhD, Memorial Sloan-Kettering Cancer Center
- Dinshaw Patel, PhD, Memorial Sloan-Kettering Cancer Center
Abstract