Seventeenth and Final Starr Cancer Consortium Grant Competition

Competing Project Renewal Awards

  • Modifiers of BRCA2 tumor suppressor loss of function: FIGNL1 as an anti-recombinase

    Principal Investigator:

      • Maria Jasin, PhD – Memorial Sloan Kettering Cancer Center

    Co-Principal Investigator:

      • Tarun Kapoor, PhD – The Rockefeller University

        • Abstract 

New Awards

  • Interrogation of chromatin dynamics of pancreas cancer cell state transitions in 4D

    Principal Investigator:

      • Tuomas Tammela, MD, PhD – Memorial Sloan Kettering Cancer Center

    Co-Principal Investigators:

      • Eftychia (Effie) Apostolu, PhD – Weill Cornell Medicine
      • Christina Leslie, PhD – Memorial Sloan Kettering Cancer Center

        • Abstract 
  • Prostate cancer non-neuroendocrine lineage plasticity: detection using multimodal integration and immunotherapeutic targeting

    Principal Investigator:

      • Ekta Khurana, PhD – Weill Cornell Medicine

    Co-Principal Investigators:

      • Francisco Sanchez-Vega, PhD – Memorial Sloan Kettering Cancer Center
      • Yu Chen, MD, PhD – Memorial Sloan Kettering Cancer Center
      • Roberta Zappasodi, PhD – Weill Cornell Medicine

        • Abstract 
  • Elucidating the clonal and microenvironmental determinants of B cell lymphomagenesis

    Principal Investigator:

      • Fei Chen, PhD – The Broad Institute of MIT and Harvard

    Co-Principal Investigators:

      • Caroline Uhler, PhD – The Broad Institute of MIT and Harvard
      • Ari Melnick, MD – Weill Cornell Medicine
      • Gabriel Victora, PhD – The Rockefeller University

        • Abstract 
  • Elucidating and targeting the resistant leukemia stem cell niche using high-resolution in situ protein interactomics and surfaceomics in human bone marrow tissue

    Principal Investigator:

      • Jacob Geri, PhD – Weill Cornell Medicine

    Co-Principal Investigator:

      • Alex Kentsis, MD, PhD – Memorial Sloan Kettering Cancer Center

        • Abstract 
  • Deciphering the impact of 2’-O-methylation on lung cancer growth and treatment response

    Principal Investigator:

      • Aaron Hata, MD, PhD – The Broad Institute of MIT and Harvard

    Co-Principal Investigators:

      • Samie Jaffrey, MD, PhD – Weill Cornell Medicine
      • Karen Adelman, PhD – The Broad Institute of MIT and Harvard

        • Abstract 
  • Role of cereblon and its endogenous substrates on therapeutic efficacy in acute myeloid leukemia

    Principal Investigator:

      • Christina Woo, PhD – The Broad Institute of MIT and Harvard

    Co-Principal Investigator:

      • Michael Kharas, PhD – Memorial Sloan Kettering Cancer Center

        • Abstract 
  • Identifying therapeutically targetable vulnerabilities induced by (R)-2HG in IDH2-mutant AML

    Principal Investigator:

      • Julie-Aurore Losman, MD, PhD – The Broad Institute of MIT and Harvard

    Co-Principal Investigator:

      • Andrew Intlekofer, MD, PhD – Memorial Sloan Kettering Cancer Center

        •  Abstract 
  • Modulating inflammation to eradicate clonal stem cells

    Principal Investigator:

      • Anna Nam, MD – Weill Cornell Medicine

    Co-Principal Investigator:

      • Leonard Zon, MD – The Broad Institute of MIT and Harvard

        •  Abstract  
  • Characterizing the role of structural genomic instability in generating actionable neoantigens in pediatric solid tumors

    Principal Investigator:

      • Elli Papaemmanuil, PhD – Memorial Sloan Kettering Cancer Center

    Co-Principal Investigators:

      • Christopher Klebanoff, MD – Memorial Sloan Kettering Cancer Center
      • Taha Merghoub, PhD – Weill Cornell Medicine

        •  Abstract